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Drug and Alcohol Dependence Volume 177 , 1 August 2017, Pages 187-193 Trends in utilization of smoking cessation agents before and after the passage of FDA boxed warning in the United States Author links open overlay panel DrishtiShaha The FDA issued a black box warning (BBW) on bupropion and varenicline in 2009. We examined the trends in use of bupropion and varenicline before and after the BBW. We observed a significant decline in the use of varenicline after the passage of BBW. The BBW was not associated with decline in the use of bupropion. Passage of BBW may have a substantial impact on the utilization of certain medications. In 2009, the FDA required a black box warning (BBW) on bupropion and varenicline, the two commonly prescribed smoking cessation agents due to reports of adverse neuropsychiatric events. We investigated if there was a decline in use of bupropion and varenicline after the BBW by comparing the percent using these medications before and after BBW. We conducted a retrospective observational study using data from the Medical Expenditure Panel Survey from 2007 to 2014. The study sample consisted of adult smokers, who were advised by their physicians to quit smoking. We divided the time period into “pre-warning”, “post-warning: immediate”, and “post-warning: late.” Unadjusted analysis using chi-square tests and adjusted analyses using logistic regressions were conducted to evaluate the change in bupropion and varenicline use before and after the BBW. Secondary analyses using piecewise regression were also conducted.

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“ Google and Facebook Failed Us ,” read the Atlantic’s headline. If companies like Google and Facebook rely too much on human intervention, they face accusations of bias, and it’s a slippery slope to being considered as media owners rather than the passive platforms they would prefer to be. But, as we keep seeing time and time again—with brand safety, fake news, anti-Semitic ad targeting—relying on algorithms alone is a clearly flawed approach. All this comes as scrutiny already is being poured on digital platforms for making it too easy for Russian-backed entities to spread manipulative information in the buildup to the U.S. presidential election. Facebook yesterday estimated 10 million users saw ads it discovered had been paid for by suspected Russian-backed accounts. The company presented congressional investigators with data on thousands of ads bought by Russian actors before and after the election. Facebook also said it plans to add 1,000 new workers to review ads on the platform. Over at Twitter, one of the focal points as Congress and others focus on Russia’s alleged use of social media to influence the election is the prevalence of bots on the platform , which can be commandeered to disseminate disingenuous information. If you thought the days of Big Tobacco ads on mainstream media were over, think again. At least temporarily.

OPP lay charges in Toronto-area tobacco bust Oct 3, 2017 - Northumberland News Click one of the buttons below or search. Here you can find useful examples and description about searching the news archive. Read it carefully to get the best results. If you need more help, please contact us. Searching is case insensitive. Words music and mUSIC return the same results. Some of the common words like the, is, etc. are not included in your search. The symbol "|" stands for OR and symbol "&" stands for AND.

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